Gevorg Grigoryan

Academic Appointments
  • Associate Professor of Computer Science

  • Adjunct Associate Professor of Biological Sciences

  • Adjunct Associate Professor of Chemistry

I am inspired by proteins. I would like to understand how each protein's function is encoded in its molecular structure and amino-acid sequence. This is a highly interdisciplinary pursuit, involving concepts from biology, physics, mathematics, computer science, and chemistry. Understanding the language of proteins will lead to cures for human diseases and will teach us how to engineer smart novel materials.

Contact

Sudikoff 113
HB 6211

Education

  • B.S. University of Maryland Baltimore County
  • Ph.D. Massachusetts Institute of Technology

Selected Publications

  • "Single methyl groups can act as toggle switches to specify transmembrane protein-protein interactions", L. He, H. Steinocher, A. Shelar, E. B. Cohen, E. N. Heim, B. B. Kragelund, G. Grigoryan, D. DiMaio, eLife6: e27701, 2017 [DOI].

  • "Sequence statistics of tertiary structural motifs reflect protein stability", F. Zheng, G. Grigoryan*, PLoS ONE12(5): e0178272, 2017 [PubMED] [DOI].

  • "Protein Structural Motifs in Prediction and Design", C. O. Mackenzie, G. GrigoryanCurrent Opinion in Structural Biology44: 161-167, 2017 [PubMED] [DOI].

  • "Design of self-assembling transmembrane helical bundles to elucidate principles required for membrane protein folding and ion transport", N. H. Joh, G. Grigoryan, Y. Wu, W. F. DeGrado, Philosophical Transactions B372(1726): 20160214, 2017 [PubMED] [DOI].

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